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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
20/06/2022 |
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Actualizado : |
20/06/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
UZAL, F.A.; GIANNITTI, F.; ASIN, J. |
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Afiliación : |
FRANCISCO A. UZAL, California Animal Health and Food Safety, University of California-Davis, San Bernardino, CA 92408, USA.; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JAVIER ASIN, California Animal Health and Food Safety, University of California-Davis, San Bernardino, CA 92408, USA. |
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Título : |
Yellow Lamb Disease (Clostridium perfringens Type A Enterotoxemia of Sheep): A Review. |
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Fecha de publicación : |
2022 |
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Fuente / Imprenta : |
Animals 2022, 12, 1590. Open Access. Doi: https://doi.org/10.3390/ani12121590 |
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Idioma : |
Inglés |
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Notas : |
Article history:Received: 12 May 2022 / Revised: 16 June 2022 / Accepted: 16 June 2022 / Published: 20 June 2022. |
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Contenido : |
bstract: Yellow lamb disease is an infrequent disease in sheep for which there is scant literature, and that has been reported in the US, Australia, New Zealand, South Africa and Europe, although anecdotal evidence indicates that it may have also been diagnosed in South America. The disease is produced by some strains of Clostridium perfringens type A that produce unusually high levels of alpha- toxin. Because C. perfringens type A is ubiquitous and is found in the intestine of most clinically healthy sheep, diagnosis of yellow lamb disease is challenging and requires quantitating the amount of this microorganism present in feces and/or intestinal content. Clinically, yellow lamb disease is characterized by depression, anemia, icterus and hemoglobinuria. Occasionally, sudden death may occur. Gross findings include generalized icterus, red urine in the bladder, enlarged, pale, and friable spleen, enlarged liver with an acinar pattern, and dark, swollen kidneys. Microscopically,
yellow lamb disease is characterized by centrilobular necrosis of the liver, hemoglobinuria-associated acute tubular injury, splenic congestion, pulmonary congestion and edema. Although there are no vaccines specifically designed to prevent yellow lamb disease, several vaccines against the different types of C. perfringens may afford at least some level of protection against yellow lamb disease. |
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Palabras claves : |
Alpha toxin; Clostridium perfringens type A; Icterus; PLATAFORMA DE SALUD ANIMAL; Yellow lamb disease. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16524/1/animals-12-01590.pdf
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Marc : |
LEADER 02160naa a2200217 a 4500
001 1063332
005 2022-06-20
008 2022 bl uuuu u00u1 u #d
100 1 $aUZAL, F.A.
245 $aYellow Lamb Disease (Clostridium perfringens Type A Enterotoxemia of Sheep)$bA Review.$h[electronic resource]
260 $c2022
500 $aArticle history:Received: 12 May 2022 / Revised: 16 June 2022 / Accepted: 16 June 2022 / Published: 20 June 2022.
520 $abstract: Yellow lamb disease is an infrequent disease in sheep for which there is scant literature, and that has been reported in the US, Australia, New Zealand, South Africa and Europe, although anecdotal evidence indicates that it may have also been diagnosed in South America. The disease is produced by some strains of Clostridium perfringens type A that produce unusually high levels of alpha- toxin. Because C. perfringens type A is ubiquitous and is found in the intestine of most clinically healthy sheep, diagnosis of yellow lamb disease is challenging and requires quantitating the amount of this microorganism present in feces and/or intestinal content. Clinically, yellow lamb disease is characterized by depression, anemia, icterus and hemoglobinuria. Occasionally, sudden death may occur. Gross findings include generalized icterus, red urine in the bladder, enlarged, pale, and friable spleen, enlarged liver with an acinar pattern, and dark, swollen kidneys. Microscopically, yellow lamb disease is characterized by centrilobular necrosis of the liver, hemoglobinuria-associated acute tubular injury, splenic congestion, pulmonary congestion and edema. Although there are no vaccines specifically designed to prevent yellow lamb disease, several vaccines against the different types of C. perfringens may afford at least some level of protection against yellow lamb disease.
653 $aAlpha toxin
653 $aClostridium perfringens type A
653 $aIcterus
653 $aPLATAFORMA DE SALUD ANIMAL
653 $aYellow lamb disease
700 1 $aGIANNITTI, F.
700 1 $aASIN, J.
773 $tAnimals 2022, 12, 1590. Open Access. Doi: https://doi.org/10.3390/ani12121590
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Registro original : |
INIA La Estanzuela (LE) |
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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
11/09/2014 |
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Actualizado : |
24/06/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
A - 1 |
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Autor : |
SOUZA, A.L.A.; DÍAZ DELLAVALLE, P.; CABRERA, A.; LARRAÑAGA, P.; DALLA RIZZA, M.; DE-SIMONE, S.G. |
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Afiliación : |
PAOLA ALEXANDRA DIAZ DELLAVALLE, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; ANDREA CECILIA CABRERA BARRIOS, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay; MARCO DALLA RIZZA VILARO, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
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Título : |
Antimicrobial activity of pleurocidin is retained in Plc-2, a C-terminal 12-amino acid fragment. |
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Fecha de publicación : |
2013 |
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Fuente / Imprenta : |
Peptides, 2013, v.45, p.78-84. |
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ISSN : |
0196-9781 |
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DOI : |
10.1016/j.peptides.2013.03.030 |
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Idioma : |
Inglés |
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Contenido : |
ABSTRACT.
An analysis of a series of five peptides composed of various portions of the pleurocidin (Plc) sequence identified a l2-amino acid fragment from the C-terminus of Plc, designated Plc-2, as the smallest fragment that retained a antimicrobial activity comparable to that of the parent compound. MIC tests in vitro with low-ionic-strength medium showed that Plc-2 has potent activity against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus but not against Enterococcus faecalis. The antifungal activity of the synthetic peptides against phytopathogenic fungi, such as Fusarium oxysporum, Colletotrichum sp., Aspergillus niger and Alternaria sp., also identified Plc-2 as a biologically active peptide. Microscopy studies of fluorescently stained fungi treated with Plc-2 demonstrated that cytoplasmic and nuclear membranes were compromised in all strains of phytopathogenic fungi tested. Together, these results identify Plc-2 as a potential antimicrobial agent with similar properties to its parent compound, pleurocidin. In addition, it demonstrated that the KHVGKAALTHYL residues are critical for the antimicrobial activity described for pleurocidin.
© 2013 Elsevier Inc. All rights reserved. |
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Thesagro : |
ALTERNARIA; HONGOS; PÉPTIDOS. |
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Asunto categoría : |
H01 Protección de plantas - Aspectos generales |
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Marc : |
LEADER 01911naa a2200241 a 4500
001 1050151
005 2021-06-24
008 2013 bl uuuu u00u1 u #d
022 $a0196-9781
024 7 $a10.1016/j.peptides.2013.03.030$2DOI
100 1 $aSOUZA, A.L.A.
245 $aAntimicrobial activity of pleurocidin is retained in Plc-2, a C-terminal 12-amino acid fragment.$h[electronic resource]
260 $c2013
520 $aABSTRACT. An analysis of a series of five peptides composed of various portions of the pleurocidin (Plc) sequence identified a l2-amino acid fragment from the C-terminus of Plc, designated Plc-2, as the smallest fragment that retained a antimicrobial activity comparable to that of the parent compound. MIC tests in vitro with low-ionic-strength medium showed that Plc-2 has potent activity against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus but not against Enterococcus faecalis. The antifungal activity of the synthetic peptides against phytopathogenic fungi, such as Fusarium oxysporum, Colletotrichum sp., Aspergillus niger and Alternaria sp., also identified Plc-2 as a biologically active peptide. Microscopy studies of fluorescently stained fungi treated with Plc-2 demonstrated that cytoplasmic and nuclear membranes were compromised in all strains of phytopathogenic fungi tested. Together, these results identify Plc-2 as a potential antimicrobial agent with similar properties to its parent compound, pleurocidin. In addition, it demonstrated that the KHVGKAALTHYL residues are critical for the antimicrobial activity described for pleurocidin. © 2013 Elsevier Inc. All rights reserved.
650 $aALTERNARIA
650 $aHONGOS
650 $aPÉPTIDOS
700 1 $aDÍAZ DELLAVALLE, P.
700 1 $aCABRERA, A.
700 1 $aLARRAÑAGA, P.
700 1 $aDALLA RIZZA, M.
700 1 $aDE-SIMONE, S.G.
773 $tPeptides, 2013$gv.45, p.78-84.
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